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Follow the following links for more information on telomere science:


Telomeres in the NEWS
  • February 15, 2008, Blood, Vol. 111, No. 4, pp. 1759-1766:
    ASH 50TH ANNIVERSARY REVIEW on Telomeres, stem cells, and hematology
  • January 29, 2008, BBC NEWS: Sedentary life 'speeds up ageing'
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    Related Peer-Reviewed Scientific Publications
  • 1. Baerlocher, G. M., Vulto, I., de Jong, G. & Lansdorp, P. M. Flow cytometry and FISH to measure the average length of telomeres (flow FISH). Nat Protoc 1, 2365-76 (2006).
  • 2. Alter, B. P. et al. Very short telomere length by flow FISH identifies patients with Dyskeratosis Congenita. Blood (2007).
  • 3. Armanios, M. Y. et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N Engl J Med 356, 1317-26 (2007).
  • 4. Ly, H. et al. Functional characterization of telomerase RNA variants found in patients with hematologic disorders. Blood 105, 2332-9 (2005).
  • 5. Ly, H. et al. Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita. Blood 106, 1246-52 (2005).
  • 6. Yamaguchi, H. et al. Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med 352, 1413-24 (2005).
  • 7. Savage S.S.,Giri N, Baerlocher, G.M., Orr, N., Lansdorp P.M., and Alter, B.P. TINF2, a Component of the Shelterin Telomere Protection Complex, is Mutated in Dyskeratosis Congenita. Am. J. Hum. Gen. 82(2): 501-9 (2008).
  • 8. Fogarty, P. F. et al. Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA. Lancet 362, 1628-30 (2003).
  • 9. Baerlocher, G. M., Rice, K., Vulto, I. & Lansdorp, P. M. Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age. Aging Cell 6, 121-3 (2007).
  • 10. Rufer, N. et al. Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. Blood 97, 575-7 (2001).
  • 11. Rufer, N. et al. Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med 190, 157-67 (1999).


    • Helpful Links
  • Dr. Peter M. Lansdorp's Flow FISH Laboratory
  • Search the telomere literature database